guanylate cyclase activator 1B (retina)
Symbol
GUCA1B
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq, Nov 2009]
Orthologs
| Symbol | Species | |
|---|---|---|
| guca1b | Danio rerio | |
| Guca1b | Mus musculus | |
| Guca1b | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0007168 | receptor guanylyl cyclase signaling pathway | biological_process | |
| GO:0007267 | cell-cell signaling | biological_process | |
| GO:0007589 | body fluid secretion | biological_process | |
| GO:0007601 | visual perception | biological_process | |
| GO:0007602 | phototransduction | biological_process | |
| GO:0031282 | regulation of guanylate cyclase activity | biological_process | |
| GO:0043085 | positive regulation of catalytic activity | biological_process | |
| GO:0050896 | response to stimulus | biological_process | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0005509 | calcium ion binding | molecular_function | |
| GO:0008048 | calcium sensitive guanylate cyclase activator activity | molecular_function | |
| GO:0030249 | guanylate cyclase regulator activity | molecular_function | |