delta-like 1 (Drosophila)

Symbol

DLL1 (may also be known as: None)

Organism

Human

Description

DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
dld Danio rerio
Dll1 Mus musculus
Dll1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3803 Gene expression of DLL1 increases with age Molecular skin Human DLL1 —

GO Terms

GO IDGO TermGO Category
GO:0001709 cell fate determination biological_process
GO:0001757 somite specification biological_process
GO:0007219 Notch signaling pathway biological_process
GO:0007220 Notch receptor processing biological_process
GO:0007267 cell-cell signaling biological_process
GO:0007275 multicellular organismal development biological_process
GO:0007368 determination of left/right symmetry biological_process
GO:0007386 compartment pattern specification biological_process
GO:0030097 hemopoiesis biological_process
GO:0030154 cell differentiation biological_process
GO:0030155 regulation of cell adhesion biological_process
GO:0045608 negative regulation of auditory receptor cell differentiation biological_process
GO:0045638 negative regulation of myeloid cell differentiation biological_process
GO:0045665 negative regulation of neuron differentiation biological_process
GO:0048839 inner ear development biological_process
GO:0050767 regulation of neurogenesis biological_process
GO:0072014 proximal tubule development biological_process
GO:0072070 loop of Henle development biological_process
GO:0097150 neuronal stem cell maintenance biological_process
GO:0005576 extracellular region cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral to plasma membrane cellular_component
GO:0031410 cytoplasmic vesicle cellular_component
GO:0005112 Notch binding molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0005515 protein binding molecular_function