malonyl CoA:ACP acyltransferase (mitochondrial)
Symbol
MCAT
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012]
Orthologs
| Symbol | Species | |
|---|---|---|
| C50D2.9 | Caenorhabditis elegans | |
| beg | Drosophila melanogaster | |
| mcat | Danio rerio | |
| Mcat | Mus musculus | |
| Mcat | Rattus norvegicus | |
| mct1 | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0006633 | fatty acid biosynthetic process | biological_process |
| GO:0008152 | metabolic process | biological_process |
| GO:0005739 | mitochondrion | cellular_component |
| GO:0004314 | [acyl-carrier-protein] S-malonyltransferase activity | molecular_function |
| GO:0005488 | binding | molecular_function |
| GO:0016740 | transferase activity | molecular_function |