gamma-glutamyltransferase 5
Symbol
GGT5
(may also be known as: None)
Organism
Human
Description
This gene is a member of a gene family that encodes gamma-glutamyl transpeptidase enzymes. This enzyme consists of a heavy and a light chain, and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesn't convert synthetic substrates that are commonly used to assay gamma-glutamyl transpeptidase. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| ggt5a | Danio rerio | |
| Ggt5 | Mus musculus | |
| Ggt5 | Rattus norvegicus | |
| ECM38 | Saccharomyces cerevisiae |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006520 | cellular amino acid metabolic process | biological_process | |
| GO:0006692 | prostanoid metabolic process | biological_process | |
| GO:0006749 | glutathione metabolic process | biological_process | |
| GO:0006750 | glutathione biosynthetic process | biological_process | |
| GO:0006954 | inflammatory response | biological_process | |
| GO:0008152 | metabolic process | biological_process | |
| GO:0019370 | leukotriene biosynthetic process | biological_process | |
| GO:0044281 | small molecule metabolic process | biological_process | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0031362 | anchored to external side of plasma membrane | cellular_component | |
| GO:0003840 | gamma-glutamyltransferase activity | molecular_function | |
| GO:0016740 | transferase activity | molecular_function | |
| GO:0016746 | transferase activity, transferring acyl groups | molecular_function | |
| GO:0016787 | hydrolase activity | molecular_function | |