RNA exonuclease 2
Symbol
REXO2
(may also be known as: None)
Organism
Human
Description
This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]
Orthologs
| Symbol | Species | |
|---|---|---|
| C08B6.8 | Caenorhabditis elegans | |
| CG10214 | Drosophila melanogaster | |
| smfn | Danio rerio | |
| Rexo2 | Mus musculus | |
| Rexo2 | Rattus norvegicus | |
| REX2 | Saccharomyces cerevisiae | |
| rex2 | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006139 | nucleobase-containing compound metabolic process | biological_process | |
| GO:0009117 | nucleotide metabolic process | biological_process | |
| GO:0005622 | intracellular | cellular_component | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005730 | nucleolus | cellular_component | |
| GO:0005739 | mitochondrion | cellular_component | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0003676 | nucleic acid binding | molecular_function | |
| GO:0004527 | exonuclease activity | molecular_function | |
| GO:0008408 | 3'-5' exonuclease activity | molecular_function | |