fibronectin type III domain containing 5
Symbol
FNDC5
(may also be known as: None)
Organism
Human
Description
This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Orthologs
| Symbol | Species | |
|---|---|---|
| fndc5a | Danio rerio | |
| Fndc5 | Mus musculus | |
| Fndc5 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2957 | Gene expression of FNDC5 decreases with age | Molecular | adipose tissue | Human | FNDC5 | — |
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0005576 | extracellular region | cellular_component |
| GO:0005777 | peroxisome | cellular_component |
| GO:0005778 | peroxisomal membrane | cellular_component |
| GO:0005886 | plasma membrane | cellular_component |
| GO:0016021 | integral to membrane | cellular_component |
| GO:0005179 | hormone activity | molecular_function |