LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)

Symbol

LSM5 (may also be known as: None)

Organism

Human

Description

Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]

Orthologs

SymbolSpecies
lsm-5 Caenorhabditis elegans
CG6610 Drosophila melanogaster
zgc:171959 Danio rerio
Lsm5 Mus musculus
LOC679753 Rattus norvegicus
LSM5 Saccharomyces cerevisiae
lsm5 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2097 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) decreases with age Molecular ovary Human LSM5 66.3% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay biological_process
GO:0006397 mRNA processing biological_process
GO:0008380 RNA splicing biological_process
GO:0010467 gene expression biological_process
GO:0016070 RNA metabolic process biological_process
GO:0016071 mRNA metabolic process biological_process
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay biological_process
GO:0005634 nucleus cellular_component
GO:0005829 cytosol cellular_component
GO:0030529 ribonucleoprotein complex cellular_component
GO:0003723 RNA binding molecular_function
GO:0005515 protein binding molecular_function