kinesin family member 1B

Symbol

KIF1B (may also be known as: None)

Organism

Human

Description

This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
unc-104 Caenorhabditis elegans
unc-104 Drosophila melanogaster
kif1b Danio rerio
Kif1b Mus musculus
Kif1b Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3706 Gene expression of KIF1B increases with age Molecular skin Human KIF1B —
DAA2095 kinesin family member 1B decreases with age Molecular ovary Human KIF1B 43.2% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006200 ATP catabolic process biological_process
GO:0006915 apoptotic process biological_process
GO:0007018 microtubule-based movement biological_process
GO:0007270 neuron-neuron synaptic transmission biological_process
GO:0007274 neuromuscular synaptic transmission biological_process
GO:0008089 anterograde axon cargo transport biological_process
GO:0030705 cytoskeleton-dependent intracellular transport biological_process
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005874 microtubule cellular_component
GO:0005875 microtubule associated complex cellular_component
GO:0030659 cytoplasmic vesicle membrane cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0003777 microtubule motor activity molecular_function
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0016887 ATPase activity molecular_function
GO:0019894 kinesin binding molecular_function