fibroblast growth factor receptor 3

Symbol

FGFR3 (may also be known as: CEK2, JTK4)

Organism

Human

Orthologs

SymbolSpecies
fgfr3 Danio rerio
Fgfr3 Mus musculus
Fgfr3 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA85 fibroblast growth factor receptor 3 Molecular brain Human FGFR3 13.0% Increase Gene Expression Level
DAA3136 Gene expression of FGFR3 increases with age Molecular skin Human FGFR3 —

GO Terms

GO IDGO TermGO Category
GO:0000165 MAPKKK cascade biological_process
GO:0001501 skeletal system development biological_process
GO:0001958 endochondral ossification biological_process
GO:0002062 chondrocyte differentiation biological_process
GO:0003416 endochondral bone growth biological_process
GO:0007259 JAK-STAT cascade biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0008286 insulin receptor signaling pathway biological_process
GO:0008543 fibroblast growth factor receptor signaling pathway biological_process
GO:0010518 positive regulation of phospholipase activity biological_process
GO:0018108 peptidyl-tyrosine phosphorylation biological_process
GO:0035988 chondrocyte proliferation biological_process
GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein biological_process
GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein biological_process
GO:0042981 regulation of apoptotic process biological_process
GO:0043410 positive regulation of MAPKKK cascade biological_process
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity biological_process
GO:0046777 protein autophosphorylation biological_process
GO:0048640 negative regulation of developmental growth biological_process
GO:0060349 bone morphogenesis biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:0070977 bone maturation biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral to plasma membrane cellular_component
GO:0005925 focal adhesion cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0016023 cytoplasmic membrane-bounded vesicle cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function
GO:0004872 receptor activity molecular_function
GO:0005007 fibroblast growth factor-activated receptor activity molecular_function
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0017134 fibroblast growth factor binding molecular_function