Fc fragment of IgG, receptor, transporter, alpha
Symbol
FCGRT
(may also be known as: None)
Organism
Human
Description
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Orthologs
| Symbol | Species | |
|---|---|---|
| Fcgrt | Mus musculus | |
| Fcgrt | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2286 | Fc fragment of IgG, receptor, transporter, alpha increases with age | Molecular | parietal lobe | Human | FCGRT | 76.7% Increase Gene Expression Level | |
| DAA2294 | Fc fragment of IgG, receptor, transporter, alpha increases with age | Molecular | frontal lobe | Human | FCGRT | 89.3% Increase Gene Expression Level |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006955 | immune response | biological_process | |
| GO:0007565 | female pregnancy | biological_process | |
| GO:0019882 | antigen processing and presentation | biological_process | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0042612 | MHC class I protein complex | cellular_component | |
| GO:0004872 | receptor activity | molecular_function | |
| GO:0019864 | IgG binding | molecular_function | |
| GO:0030881 | beta-2-microglobulin binding | molecular_function | |