Fc fragment of IgG, low affinity IIIb, receptor (CD16b)

Symbol

FCGR3B (may also be known as: None)

Organism

Human

Description

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2160 Fc fragment of IgG, low affinity IIIb, receptor (CD16b) increases with age Molecular hippocampus Human FCGR3B 647.0% Increase Gene Expression Level
DAA2162 Fc fragment of IgG, low affinity IIIb, receptor (CD16b) increases with age Molecular frontal lobe Human FCGR3B 261.1% Increase Gene Expression Level
DAA2161 Fc fragment of IgG, low affinity IIIb, receptor (CD16b) increases with age Molecular parietal lobe Human FCGR3B 404.6% Increase Gene Expression Level
DAA2278 Fc fragment of IgG, low affinity IIIb, receptor (CD16b) increases with age Molecular hippocampus Human FCGR3B 80.8% Increase Gene Expression Level
DAA2285 Fc fragment of IgG, low affinity IIIb, receptor (CD16b) increases with age Molecular parietal lobe Human FCGR3B 131.1% Increase Gene Expression Level
DAA2293 Fc fragment of IgG, low affinity IIIb, receptor (CD16b) increases with age Molecular frontal lobe Human FCGR3B 52.1% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006955 immune response biological_process
GO:0005576 extracellular region cellular_component
GO:0005886 plasma membrane cellular_component
GO:0031225 anchored to membrane cellular_component
GO:0004872 receptor activity molecular_function
GO:0019864 IgG binding molecular_function