eukaryotic translation elongation factor 1 alpha 2
Symbol
EEF1A2
(may also be known as: None)
Organism
Human
Description
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. [provided by RefSeq, Mar 2014]
Orthologs
| Symbol | Species | |
|---|---|---|
| Ef1alpha100E | Drosophila melanogaster | |
| eef1a2 | Danio rerio | |
| Eef1a2 | Mus musculus | |
| Eef1a2 | Rattus norvegicus | |
| TEF1 | Saccharomyces cerevisiae | |
| tef1b | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006412 | translation | biological_process | |
| GO:0006916 | anti-apoptosis | biological_process | |
| GO:0010035 | response to inorganic substance | biological_process | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005853 | eukaryotic translation elongation factor 1 complex | cellular_component | |
| GO:0043025 | neuronal cell body | cellular_component | |
| GO:0000166 | nucleotide binding | molecular_function | |
| GO:0003746 | translation elongation factor activity | molecular_function | |
| GO:0003924 | GTPase activity | molecular_function | |
| GO:0005525 | GTP binding | molecular_function | |
| GO:0008135 | translation factor activity, nucleic acid binding | molecular_function | |