dynein, axonemal, heavy chain 8
Symbol
DNAH8
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012]
Orthologs
| Symbol | Species | |
|---|---|---|
| CG9492 | Drosophila melanogaster | |
| Dnahc8 | Mus musculus | |
| Dnah8 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0001539 | ciliary or flagellar motility | biological_process | |
| GO:0007018 | microtubule-based movement | biological_process | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005856 | cytoskeleton | cellular_component | |
| GO:0005858 | axonemal dynein complex | cellular_component | |
| GO:0005874 | microtubule | cellular_component | |
| GO:0005929 | cilium | cellular_component | |
| GO:0009434 | microtubule-based flagellum | cellular_component | |
| GO:0035085 | cilium axoneme | cellular_component | |
| GO:0000166 | nucleotide binding | molecular_function | |
| GO:0003777 | microtubule motor activity | molecular_function | |
| GO:0005524 | ATP binding | molecular_function | |
| GO:0016887 | ATPase activity | molecular_function | |