dihydrolipoamide S-acetyltransferase

Symbol

DLAT (may also be known as: PDC-E2)

Organism

Human

Orthologs

SymbolSpecies
F23B12.5 Caenorhabditis elegans
CG5261 Drosophila melanogaster
dlat Danio rerio
Dlat Mus musculus
uncharacterized_M0RA Rattus norvegicus
LAT1 Saccharomyces cerevisiae
lat1 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA368 dihydrolipoamide S-acetyltransferase Molecular skeletal muscle Human DLAT 6.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006085 acetyl-CoA biosynthetic process biological_process
GO:0006090 pyruvate metabolic process biological_process
GO:0006096 glycolysis biological_process
GO:0008152 metabolic process biological_process
GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate biological_process
GO:0030431 sleep biological_process
GO:0044281 small molecule metabolic process biological_process
GO:0005739 mitochondrion cellular_component
GO:0005759 mitochondrial matrix cellular_component
GO:0005967 mitochondrial pyruvate dehydrogenase complex cellular_component
GO:0045254 pyruvate dehydrogenase complex cellular_component
GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity molecular_function
GO:0005515 protein binding molecular_function
GO:0016746 transferase activity, transferring acyl groups molecular_function