Ras association (RalGDS/AF-6) domain family member 6
Symbol
RASSF6
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
Orthologs
| Symbol | Species | |
|---|---|---|
| Rassf | Drosophila melanogaster | |
| rassf6 | Danio rerio | |
| Rassf6 | Mus musculus | |
| Rassf6 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0007165 | signal transduction | biological_process |
| GO:0042981 | regulation of apoptotic process | biological_process |
| GO:0005515 | protein binding | molecular_function |