membrane bound O-acyltransferase domain containing 1
Symbol
MBOAT1
(may also be known as: None)
Organism
Human
Description
This gene belongs to the membrane-bound O-acetyltransferase superfamily. The encoded transmembrane protein is an enzyme that transfers organic compounds, preferably from oleoyl-CoA, to hydroxyl groups of protein targets in membranes. A translocation disrupting this gene may be associated with brachydactyly syndactyly syndrome. Alternately spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
Orthologs
| Symbol | Species | |
|---|---|---|
| oys | Drosophila melanogaster | |
| mboat1 | Danio rerio | |
| Mboat1 | Mus musculus | |
| Mboat1 | Rattus norvegicus | |
| ALE1 | Saccharomyces cerevisiae | |
| ale1 | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0008654 | phospholipid biosynthetic process | biological_process |
| GO:0016020 | membrane | cellular_component |
| GO:0016021 | integral to membrane | cellular_component |
| GO:0016747 | transferase activity, transferring acyl groups other than amino-acyl groups | molecular_function |