copper metabolism (Murr1) domain containing 1
Symbol
COMMD1
(may also be known as: None)
Organism
Human
Description
COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al., 2005 [PubMed 16267171]).[supplied by OMIM, Sep 2009]
Orthologs
| Symbol | Species | |
|---|---|---|
| commd1 | Danio rerio | |
| Commd1 | Mus musculus | |
| Commd1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0031398 | positive regulation of protein ubiquitination | biological_process | |
| GO:0032088 | negative regulation of NF-kappaB transcription factor activity | biological_process | |
| GO:0032434 | regulation of proteasomal ubiquitin-dependent protein catabolic process | biological_process | |
| GO:0055070 | copper ion homeostasis | biological_process | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005730 | nucleolus | cellular_component | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0030054 | cell junction | cellular_component | |
| GO:0031462 | Cul2-RING ubiquitin ligase complex | cellular_component | |
| GO:0005507 | copper ion binding | molecular_function | |
| GO:0005515 | protein binding | molecular_function | |
| GO:0042802 | identical protein binding | molecular_function | |
| GO:0042803 | protein homodimerization activity | molecular_function | |
| GO:0046872 | metal ion binding | molecular_function | |