carnitine palmitoyltransferase 2
Symbol
CPT2
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| cpt-2 | Caenorhabditis elegans | |
| CG2107 | Drosophila melanogaster | |
| cpt2 | Danio rerio | |
| Cpt2 | Mus musculus | |
| Cpt2 | Rattus norvegicus | |
| YAT1 | Saccharomyces cerevisiae |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006631 | fatty acid metabolic process | biological_process | |
| GO:0006635 | fatty acid beta-oxidation | biological_process | |
| GO:0006810 | transport | biological_process | |
| GO:0006853 | carnitine shuttle | biological_process | |
| GO:0044255 | cellular lipid metabolic process | biological_process | |
| GO:0044281 | small molecule metabolic process | biological_process | |
| GO:0046320 | regulation of fatty acid oxidation | biological_process | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005730 | nucleolus | cellular_component | |
| GO:0005739 | mitochondrion | cellular_component | |
| GO:0005743 | mitochondrial inner membrane | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0004095 | carnitine O-palmitoyltransferase activity | molecular_function | |
| GO:0016746 | transferase activity, transferring acyl groups | molecular_function | |