collagen, type XVI, alpha 1

Symbol

COL16A1 (may also be known as: None)

Organism

Human

Description

This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
si:dkey-27a13.3 Danio rerio
Col16a1 Mus musculus
Col16a1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3068 Gene expression of COL16A1 increases with age Molecular skin Human COL16A1 —

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1702 collagen, type XVI, alpha 1 Molecular lung Mouse Col16a1 8.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0007155 cell adhesion biological_process
GO:0007229 integrin-mediated signaling pathway biological_process
GO:0007565 female pregnancy biological_process
GO:0071230 cellular response to amino acid stimulus biological_process
GO:0005576 extracellular region cellular_component
GO:0005581 collagen cellular_component
GO:0005597 collagen type XVI cellular_component
GO:0005178 integrin binding molecular_function
GO:0005198 structural molecule activity molecular_function
GO:0005515 protein binding molecular_function