NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
Symbol
NDUFA11
(may also be known as: None)
Organism
Human
Description
This gene encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]
Orthologs
| Symbol | Species | |
|---|---|---|
| Ndufa11 | Mus musculus | |
| Ndufa11 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006810 | transport | biological_process | |
| GO:0022904 | respiratory electron transport chain | biological_process | |
| GO:0044281 | small molecule metabolic process | biological_process | |
| GO:0005739 | mitochondrion | cellular_component | |
| GO:0005743 | mitochondrial inner membrane | cellular_component | |
| GO:0005747 | mitochondrial respiratory chain complex I | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0070469 | respiratory chain | cellular_component | |