cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a)

Symbol	Species
cdkn1a	Danio rerio
CDKN1A	Homo sapiens
Cdkn1a	Rattus norvegicus

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA1742	cyclin-dependent kinase inhibitor 1A (P21)	Molecular	muscle	Mouse	Cdkn1a	14.0% Increase Gene Expression Level

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Changes associated with the orthologs of this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA444	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	Molecular	skeletal muscle	Human	CDKN1A	50.0% Increase Gene Expression Level
DAA3045	Gene expression of CDKN1A decreases with age	Molecular	skin	Human	CDKN1A	—

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GO Terms

GO ID	GO Term	GO Category
GO:0000079	regulation of cyclin-dependent protein kinase activity	biological_process
GO:0000082	G1/S transition of mitotic cell cycle	biological_process
GO:0000086	G2/M transition of mitotic cell cycle	biological_process
GO:0006974	response to DNA damage stimulus	biological_process
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	biological_process
GO:0007049	cell cycle	biological_process
GO:0007050	cell cycle arrest	biological_process
GO:0007346	regulation of mitotic cell cycle	biological_process
GO:0008285	negative regulation of cell proliferation	biological_process
GO:0009411	response to UV	biological_process
GO:0010629	negative regulation of gene expression	biological_process
GO:0016310	phosphorylation	biological_process
GO:0030308	negative regulation of cell growth	biological_process
GO:0030890	positive regulation of B cell proliferation	biological_process
GO:0031668	cellular response to extracellular stimulus	biological_process
GO:0033158	regulation of protein import into nucleus, translocation	biological_process
GO:0042326	negative regulation of phosphorylation	biological_process
GO:0043066	negative regulation of apoptotic process	biological_process
GO:0043068	positive regulation of programmed cell death	biological_process
GO:0045736	negative regulation of cyclin-dependent protein kinase activity	biological_process
GO:0045768	positive regulation of anti-apoptosis	biological_process
GO:0048146	positive regulation of fibroblast proliferation	biological_process
GO:0051726	regulation of cell cycle	biological_process
GO:0071479	cellular response to ionizing radiation	biological_process
GO:0071850	mitotic cell cycle arrest	biological_process
GO:0090398	cellular senescence	biological_process
GO:2000278	regulation of DNA biosynthetic process	biological_process
GO:2000379	positive regulation of reactive oxygen species metabolic process	biological_process
GO:0000307	cyclin-dependent protein kinase holoenzyme complex	cellular_component
GO:0005634	nucleus	cellular_component
GO:0005737	cytoplasm	cellular_component
GO:0005829	cytosol	cellular_component
GO:0070557	PCNA-p21 complex	cellular_component
GO:0004860	protein kinase inhibitor activity	molecular_function
GO:0004861	cyclin-dependent protein kinase inhibitor activity	molecular_function
GO:0005515	protein binding	molecular_function
GO:0016301	kinase activity	molecular_function
GO:0019912	cyclin-dependent protein kinase activating kinase activity	molecular_function
GO:0030332	cyclin binding	molecular_function
GO:0032403	protein complex binding	molecular_function
GO:0046872	metal ion binding	molecular_function
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cyclin-dependent kinase inhibitor 1A (P21)

Symbol

Organism

Orthologs

Links to external resources

Changes associated with this gene

Changes associated with the orthologs of this gene

GO Terms