collagen triple helix repeat containing 1
Symbol
CTHRC1
(may also be known as: None)
Organism
Human
Description
This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
Orthologs
| Symbol | Species | |
|---|---|---|
| cthrc1b | Danio rerio | |
| Cthrc1 | Mus musculus | |
| Cthrc1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0016477 | cell migration | biological_process | |
| GO:0032092 | positive regulation of protein binding | biological_process | |
| GO:0060071 | Wnt receptor signaling pathway, planar cell polarity pathway | biological_process | |
| GO:0060122 | inner ear receptor stereocilium organization | biological_process | |
| GO:0090090 | negative regulation of canonical Wnt receptor signaling pathway | biological_process | |
| GO:0090103 | cochlea morphogenesis | biological_process | |
| GO:0090177 | establishment of planar polarity involved in neural tube closure | biological_process | |
| GO:0005576 | extracellular region | cellular_component | |
| GO:0005581 | collagen | cellular_component | |
| GO:0005615 | extracellular space | cellular_component | |
| GO:0005109 | frizzled binding | molecular_function | |
| GO:0017147 | Wnt-protein binding | molecular_function | |