cytoglobin

Symbol

CYGB (may also be known as: None)

Organism

Human

Description

This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012]

Orthologs

SymbolSpecies
uncharacterized_H9GX Danio rerio
Cygb Mus musculus
Cygb Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006810 transport biological_process
GO:0006979 response to oxidative stress biological_process
GO:0015671 oxygen transport biological_process
GO:0005737 cytoplasm cellular_component
GO:0043005 neuron projection cellular_component
GO:0043025 neuronal cell body cellular_component
GO:0004601 peroxidase activity molecular_function
GO:0005344 oxygen transporter activity molecular_function
GO:0019825 oxygen binding molecular_function
GO:0020037 heme binding molecular_function
GO:0046872 metal ion binding molecular_function