acyl-CoA thioesterase 7

Symbol

ACOT7 (may also be known as: None)

Organism

Human

Description

This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants encoding distinct isoforms with different subcellular locations have been characterized. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
acot7 Danio rerio
Acot7 Mus musculus
Acot7 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3676 Gene expression of ACOT7 decreases with age Molecular skin Human ACOT7 —

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1630 acyl-CoA thioesterase 7 Molecular lung Mouse Acot7 3.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006629 lipid metabolic process biological_process
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005829 cytosol cellular_component
GO:0000062 fatty-acyl-CoA binding molecular_function
GO:0003824 catalytic activity molecular_function
GO:0004091 carboxylesterase activity molecular_function
GO:0016290 palmitoyl-CoA hydrolase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0047617 acyl-CoA hydrolase activity molecular_function