lymphatic vessel endothelial hyaluronan receptor 1

Symbol

LYVE1 (may also be known as: None)

Organism

Human

Description

This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
LOC560618 Danio rerio
Lyve1 Mus musculus
Lyve1 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006027 glycosaminoglycan catabolic process biological_process
GO:0006810 transport biological_process
GO:0006928 cellular component movement biological_process
GO:0007155 cell adhesion biological_process
GO:0007160 cell-matrix adhesion biological_process
GO:0007165 signal transduction biological_process
GO:0009611 response to wounding biological_process
GO:0009653 anatomical structure morphogenesis biological_process
GO:0005624 membrane fraction cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral to plasma membrane cellular_component
GO:0004872 receptor activity molecular_function
GO:0004888 transmembrane signaling receptor activity molecular_function
GO:0005488 binding molecular_function
GO:0005540 hyaluronic acid binding molecular_function