cartilage associated protein

Symbol

CRTAP (may also be known as: None)

Organism

Human

Description

The protein encoded by this gene is similar to the chicken and mouse CRTAP genes. The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli. Defects in this gene are associated with osteogenesis imperfecta, a connective tissue disorder characterized by bone fragility and low bone mass. [provided by RefSeq, Jul 2008]

Orthologs

Symbol	Species
crtap	Danio rerio
Crtap	Mus musculus

Links to external resources

Entrez Gene: 10491
OMIM: 605497
Ensembl: ENSG00000170275
UniProt: O75718
UniGene: Hs.517888
GeneCards

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA3620	Gene expression of CRTAP increases with age	Molecular	skin	Human	CRTAP	—

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GO Terms

GO ID	GO Term	GO Category
GO:0007283	spermatogenesis	biological_process
GO:0005576	extracellular region	cellular_component
GO:0005578	proteinaceous extracellular matrix	cellular_component
GO:0005488	binding	molecular_function