C-type lectin domain family 10, member A
Symbol
CLEC10A
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| lectin-24Db | Drosophila melanogaster |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA3618 | Gene expression of CLEC10A decreases with age | Molecular | skin | Human | CLEC10A | — | |
| DAA2867 | Gene expression of CLEC10A decreases with age | Molecular | adipose tissue | Human | CLEC10A | — |
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0006897 | endocytosis | biological_process |
| GO:0045087 | innate immune response | biological_process |
| GO:0005886 | plasma membrane | cellular_component |
| GO:0016021 | integral to membrane | cellular_component |
| GO:0005488 | binding | molecular_function |
| GO:0005529 | sugar binding | molecular_function |