actin related protein 2/3 complex, subunit 2, 34kDa
Symbol
ARPC2
(may also be known as: None)
Organism
Human
Description
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| arx-4 | Caenorhabditis elegans | |
| Arc-p34 | Drosophila melanogaster | |
| arpc2 | Danio rerio | |
| Arpc2 | Mus musculus | |
| Arpc2 | Rattus norvegicus | |
| ARC35 | Saccharomyces cerevisiae | |
| arc2 | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006928 | cellular component movement | biological_process | |
| GO:0030833 | regulation of actin filament polymerization | biological_process | |
| GO:0030838 | positive regulation of actin filament polymerization | biological_process | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005794 | Golgi apparatus | cellular_component | |
| GO:0005856 | cytoskeleton | cellular_component | |
| GO:0005885 | Arp2/3 protein complex | cellular_component | |
| GO:0005925 | focal adhesion | cellular_component | |
| GO:0015629 | actin cytoskeleton | cellular_component | |
| GO:0031252 | cell leading edge | cellular_component | |
| GO:0042995 | cell projection | cellular_component | |
| GO:0003779 | actin binding | molecular_function | |
| GO:0005200 | structural constituent of cytoskeleton | molecular_function | |
| GO:0005515 | protein binding | molecular_function | |