Chemotaxis and respiratory burst capacity in response to GM-CSF priming decreased

Physiological

Data Availability

Period at which this change occurs is not accurately known

Tissue

  • neutrophil Changes

References

  • Tortorella et al. (2007) "Age-related impairment of GM-CSF-induced signalling in neutrophils: role of SHP-1 and SOCS proteins." Ageing Res. Rev. 6(2):81-93 (PubMed)
Referencing provided by LibAge

External Links

Description

Granulocyte macrophage colony simulating factor (GM-CSF) is a cytokine associated with stimulating neutrophil functions, including: cell adhesion, phagocytosis, respiratory burst priming. Chemotaxis and respiratory burst capacity in response to GM-CSF priming is decreased with age.